| Date | Location | Result | |
| May 14, 2021 | Hammond, La. | Northwestern State 8, Sam Houston 0 | Box score |
| May 13, 2021 | Hammond, La. | McNeese 3, Sam Houston 1 | Box score |
| May 12, 2021 | Hammond, La. | Sam Houston 4, Houston Baptist 3 | Box score |
| May 08, 2021 | Huntsville, Texas | Sam Houston 9, UIW 1 | Box score |
| May 07, 2021 | Huntsville, Texas | Sam Houston 4, UIW 0 | Box score |
| May 07, 2021 | Huntsville, Texas | Sam Houston 4, UIW 0 | Box score |
| May 01, 2021 | Huntsville, Texas | Stephen F. Austin 11, Sam Houston 8 | Box score |
| Apr 30, 2021 | Huntsville, Texas | Stephen F. Austin 1, Sam Houston 0 | Box score |
| Apr 30, 2021 | Huntsville, Texas | Stephen F. Austin 3, Sam Houston 0 | Box score |
| Apr 28, 2021 | Huntsville, Texas | Sam Houston 3, Tarleton 1 | Box score |
| Apr 25, 2021 | Natchitoches, LA | Sam Houston 6, Northwestern State 1 | Box score |
| Apr 23, 2021 | Natchitoches, LA | Northwestern State 6, Sam Houston 4 | Box score |
| Apr 23, 2021 | Natchitoches, LA | Northwestern State 4, Sam Houston 3 | Box score |
| Apr 21, 2021 | Waco, Texas | Baylor 8, Sam Houston 0 | Box score |
| Apr 18, 2021 | Huntsville, Texas | Sam Houston 4, Southeastern La. 2 | Box score |
| Apr 17, 2021 | Huntsville, Texas | Sam Houston 8, Southeastern La. 0 | Box score |
| Apr 17, 2021 | Huntsville, Texas | Southeastern La. 13, Sam Houston 0 | Box score |
| Apr 14, 2021 | College Station, TX | Texas A&M 8, Sam Houston 0 | Box score |
| Apr 10, 2021 | Abilene, Texas | Sam Houston 9, Abilene Christian 5 | Box score |
| Apr 09, 2021 | Abilene, Texas | Sam Houston 9, Abilene Christian 3 | Box score |
| Apr 09, 2021 | Abilene, Texas | Sam Houston 13, Abilene Christian 10 | Box score |
| Apr 06, 2021 | Huntsville, Texas | Louisiana 8, Sam Houston 3 | Box score |
| Apr 03, 2021 | Huntsville, Texas | Sam Houston 4, Houston Baptist 1 | Box score |
| Apr 02, 2021 | Huntsville, Texas | Houston Baptist 2, Sam Houston 0 | Box score |
| Apr 02, 2021 | Huntsville, Texas | Houston Baptist 8, Sam Houston 0 | Box score |
| Mar 31, 2021 | Huntsville, Texas | UT Arlington 8, Sam Houston 1 | Box score |
| Mar 27, 2021 | Conway, Ark. | Central Arkansas 5, Sam Houston 1 | Box score |
| Mar 26, 2021 | Conway, Ark. | Central Arkansas 1, Sam Houston 0 | Box score |
| Mar 26, 2021 | Conway, Ark. | Central Arkansas 11, Sam Houston 1 | Box score |
| Mar 23, 2021 | Huntsville, Texas | Baylor 7, Sam Houston 3 | Box score |
| Mar 20, 2021 | Huntsville, Texas | Sam Houston 4, McNeese 0 | Box score |
| Mar 20, 2021 | Huntsville, Texas | Sam Houston 6, McNeese 0 | Box score |
| Mar 19, 2021 | Huntsville, Texas | Sam Houston 6, McNeese 1 | Box score |
| Mar 13, 2021 | Corpus Christi, TX | A&M-Corpus Christi 5, Sam Houston 0 | Box score |
| Mar 12, 2021 | Corpus Christi, TX | Sam Houston 6, A&M-Corpus Christi 0 | Box score |
| Mar 12, 2021 | Corpus Christi, TX | A&M-Corpus Christi 4, Sam Houston 2 | Box score |
| Mar 10, 2021 | San Marcos, TX | Texas State 6, Sam Houston 0 | Box score |
| Mar 10, 2021 | San Marcos, TX | BYU 12, Sam Houston 2 | Box score |
| Mar 07, 2021 | Norman, OK | Oklahoma 17, Sam Houston 0 | Box score |
| Mar 07, 2021 | Norman, Okla. | ULM 8, Sam Houston 6 | Box score |
| Mar 06, 2021 | Norman, Okla. | Sam Houston 5, ULM 3 | Box score |
| Mar 06, 2021 | Norman, Okla. | Missouri 10, Sam Houston 0 | Box score |
| Mar 05, 2021 | Norman, Okla. | Oklahoma 7, Sam Houston 0 | Box score |
| Mar 03, 2021 | Huntsville, Texas | Texas A&M 11, Sam Houston 5 | Box score |
| Feb 27, 2021 | San Marcos, TX | Texas State 10, Sam Houston 3 | Box score |
| Feb 27, 2021 | San Marcos, TX | Ole Miss 12, Sam Houston 0 | Box score |
| Feb 26, 2021 | Austin, Texas | Sam Houston 12, Lamar 6 | Box score |
| Feb 26, 2021 | Austin, Texas | Texas 9, Sam Houston 3 | Box score |
| Feb 24, 2021 | Huntsville, Texas | Houston 16, Sam Houston 3 | Box score |
| Feb 24, 2021 | Huntsville, Texas | Sam Houston 2, Houston 1 | Box score |